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Symbol
Name
ID

Dact1
dishevelled-binding antagonist of beta-catenin 1
MGI:1891740

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Microcephaly	Hydrocephalus	Holoprosencephaly	Tethered cord	Intellectual disability	Global developmental delay
Disease(s) Associated with DACT1
Townes-Brocks syndrome

Mouse Phenotypes		nervous system phenotype	spina bifida	abnormal dendritic spine morphology	abnormal synapse morphology	decreased miniature excitatory postsynaptic current frequency
Availability	Mouse Genotype	nervous system phenotype	spina bifida	abnormal dendritic spine morphology	abnormal synapse morphology
	Dact1^tm1.1Bnrc/Dact1^tm1.1Bnrc
	Dact1^tm1.1Bnrc/Dact1^tm1.2Bnrc Emx1^tm1(cre)Krj/Emx1⁺ (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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